DeepMatcher®

Understanding interactions between small molecules and their target proteins is crucial for drug discovery. DeepMatcher® is a compound-protein interaction (CPI) prediction platform that offers a unique opportunity to accelerate hit discovery, hit-to-lead, and lead optimization processes.
DeepMatcher® offers CPI prediction based on our proprietary biophysics-informed deep learning and large chemical spaces, thereby enabling more accurate discovery of compounds with novel structures.

DeepMatcher® has been successfully applied across protein families such as kinases, G protein coupled receptors (GPCR), and nuclear receptors.

Modularity of the DeepMatcher® platform offers a broad scope of services such as DeepMatcher®-Hit and DeepMatcher®-Lead. DeepMatcher®-Hit conducts a comprehensive screening to discover hit compounds using up to 1 billion compound library. DeepMatcher®-Lead performs hit-to-lead and lead optimization process by in silico design using a given scaffold generating 100K derivatives to improve binding affinity.